Cleveland Browns

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Bio

Isaiah McGuire is a 6'4", 266-pound left defensive end for the Cleveland Browns. The Browns selected him in the fourth round (126th overall) of the 2023 NFL Draft out of Missouri, where he recorded 103 tackles and 16.5 sacks over four years (2019-22), ranking 13th in program history. In 2024, McGuire appeared in 16 games with three starts, posting 34 tackles, three forced fumbles, and 2.5 sacks. He recorded his first career sack on Jan. 7, 2024, and later added a strip-sack of Joe Burrow on Dec. 22, 2024.

Isaiah McGuire played 17 games in 2025 with a 41% share of defensive snaps.

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Contract

T-149 of 188 · EDGE market by AAV

Career path