Sean Cuono holds the RB · Depth spot in Indiana Hoosiers’s running back room. Where he sits among the room’s front-line roles:

Sean Cuono logged a 3.0% overall usage rate in 2025.

Sean Cuono is a running back from Clearwater, Florida, who attended Clearwater Central Catholic High School after spending two prep seasons at Calvary Christian. A consensus three-star prospect, he was ranked among the top-75 running backs nationally and earned the No. 91 ranking in Florida. In his final prep year, Cuono carried 69 times for 518 yards and six touchdowns while adding four receptions for 34 yards and one score. He made his collegiate debut against Indiana State on September 12, 2025, recording 17 rushing yards on two carries. Cuono currently appears in a reserve role for the Indiana Hoosiers.